Study to evaluate the interaction between aspirin and Nexium

Exclusion Criteria

• - Involvement in the planning and/or conduct of the study (applies to both AstraZeneca staff and/or staff at the study site)
• - Previous enrolment or randomisation in the present study.
• - History of any clinically significant disease or disorder which, in the opinion of the investigator, may either put the subject at risk because of participation in the study, or influence the results or the subject's ability to participate in the study e.g. history of any bleeding disorder, excessive bruising or ongoing or history of liver disease
• - History or presence of clinically significant gastrointestinal e.e. GI ulcer, hepatic or renal disease or any other condition known to interfere with absorption, distribution, metabolism or excretion of drugs.
• - Any clinically significant illness within 4 weeks of the first administration of investigational product.